Chronic hepatitis C: future treatment
نویسندگان
چکیده
منابع مشابه
Chronic hepatitis C: future treatment
The launch of first-generation protease inhibitors (PIs) is a major step forward in HCV treatment. However, the major advance is up to now restricted to genotype 1 (GT-1) patients. The development of second-wave and second-generation PIs yields higher antiviral potency through plurigenotypic activity, more convenient daily administration, fewer side effects and, for the second-generation PIs, p...
متن کاملFuture perspectives in the treatment of chronic Hepatitis C
The main lines of research into new drugs and treatment strategies against type C viral hepatitis are described. This disease is a major public health problem, with more than 700,000 people affected by the illness in Spain and with a high degree of prevalence amongst prison inmates. Limitations on current treatment for viral hepatitis C have led to research into new drugs in the form of two mai...
متن کامل[Future perspective in the treatment of chronic hepatitis C].
The main lines of research into new drugs and treatment strategies against type C viral hepatitis are described. This disease is a major public health problem, with more than 700,000 people affected by the illness in Spain and with a high degree of prevalence amongst prison inmates. Limitations on current treatment for viral hepatitis C have led to research into new drugs in the form of two mai...
متن کاملTreatment of chronic hepatitis C.
Treatment for chronic hepatitis C has changed over the past years achieving higher response rates. The combination treatment with pegylated interferon-a and ribavirin is tailored based on the on-treatment virological responses. With this response-guided therapy, the overall sustained virological response rate is about 55%. Many new antivirals are currently under investigation and some will be c...
متن کاملHistorical treatment of chronic hepatitis B and chronic hepatitis C.
Interferon is currently considered to be the only accepted effective treatment for chronic viral hepatitis. A history of the treatment of chronic hepatitis B and C before the use of interferon is presented here. Hepatitis B virus does not seem to be directly cytopathic and the disease is known to be modulated largely by the host's immune response. Experience with immunosuppressant and immunosti...
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ژورنال
عنوان ژورنال: Clinical Pharmacology: Advances and Applications
سال: 2014
ISSN: 1179-1438
DOI: 10.2147/cpaa.s30338